Can We Explain All Suffering?
Perhaps the suffering most difficult to understand is that which seems to come out of nowhere and for no discernible reason.
We must realize that individual tragedies may occur over which we have no control and that are impossible for us to foresee. In such instances the Scriptures encourage us to pray, asking God to remove or relieve the problem or help us deal with the difficulty and learn from it.
Our Creator in His wisdom doesn't always give us the answer we want. Rarely does He reveal the specific reason for the decision He makes. Yet He always has a good reason.
For example, God delivered the apostle Paul from many trials, but in at least one He declined to intervene in spite of Paul's fervent prayers (2 Corinthians 12:7-10). On this occasion the response to Paul was, "My grace is sufficient for you, for My strength is made perfect in weakness."
In this instance, strengthening an aspect of Paul's spiritual perspective or character was ultimately more important than his personal comfort.
This example should help us understand that God's perspective is different from ours (see Isaiah 55:8-9; 2 Peter 3:8.. He sometimes places the character lessons we should learn in difficult circumstances above our physical and mental comfort.
At such times we may think God doesn't hear our prayers,but He does. It's just that we often don't want to accept that His answer is "no" or "not yet"—or, as in the case of the apostle Paul, "I have something better in mind for you."
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http://www.ucg.org/booklets/AS/explain-suffering.asp